Overview of inhalation toxicology.

Biomass smoke exposures: toxicology and animal study design.

The International Biomass Smoke Health Effects (IBSHE) conference was convened in Missoula, MT, to define our current knowledge of smoke exposure and the potential health effects. In an effort to ascertain the relative health effects of an exposure to biomass smoke, numerous studies have utilized either animal or in vitro systems. A wide variety of systems that have been employed ranged from mo...

Hydrogen cyanide related deaths and detection in the blood.

Abstracts In Vitro Toxicology Society Annual Meeting November 10–11, 2015 Birmingham, United Kingdom

In Vitro Toxicology Society Annual Meeting November 10–11, 2015 Birmingham, United Kingdom These abstracts were presented at the 2015 annual meeting of the UK In Vitro Toxicology Society (IVTS). The meeting was hosted at Birmingham, UK on November 10–11, 2015. The main session topics included hepatoxicology, inhalation toxicology, developmental and reproductive toxicology, and neurotoxicology. ...

Understanding mechanisms of inhaled toxicants: implications for replacing default factors with chemical-specific data.

Assessing risk of inhaled materials is a challenging endeavor because of the profound interspecies differences in respiratory tract anatomy, physiology, and biochemistry. Recent advances in the availability of mechanistic data and mathematical models for describing dosimetry behavior of particles and gases has lead to improvements in default approaches to risk assessment of inhaled materials. A...

Dosimetry of particles in laboratory animals and humans in relationship to issues surrounding lung overload and human health risk assessment: a critical review.